Does METHOTREXATE Cause Multiple-drug resistance? 142 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 142 reports of Multiple-drug resistance have been filed in association with METHOTREXATE (Methotrexate). This represents 0.1% of all adverse event reports for METHOTREXATE.
142
Reports of Multiple-drug resistance with METHOTREXATE
0.1%
of all METHOTREXATE reports
10
Deaths
27
Hospitalizations
How Dangerous Is Multiple-drug resistance From METHOTREXATE?
Of the 142 reports, 10 (7.0%) resulted in death, 27 (19.0%) required hospitalization, and 5 (3.5%) were considered life-threatening.
Is Multiple-drug resistance Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 142 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Multiple-drug resistance?
LEVETIRACETAM (1,378)
LACOSAMIDE (739)
VALPROIC ACID (622)
TOPIRAMATE (521)
CLOBAZAM (486)
LAMOTRIGINE (418)
PHENOBARBITAL (406)
PHENYTOIN (337)
CARBAMAZEPINE (299)
PERAMPANEL (258)
Which METHOTREXATE Alternatives Have Lower Multiple-drug resistance Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA