Does ISONIAZID Cause Pancytopenia? 85 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 85 reports of Pancytopenia have been filed in association with ISONIAZID (Isoniazid). This represents 1.1% of all adverse event reports for ISONIAZID.
85
Reports of Pancytopenia with ISONIAZID
1.1%
of all ISONIAZID reports
33
Deaths
46
Hospitalizations
How Dangerous Is Pancytopenia From ISONIAZID?
Of the 85 reports, 33 (38.8%) resulted in death, 46 (54.1%) required hospitalization, and 21 (24.7%) were considered life-threatening.
Is Pancytopenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ISONIAZID. However, 85 reports have been filed with the FAERS database.
What Other Side Effects Does ISONIAZID Cause?
Drug-induced liver injury (766)
Drug ineffective (607)
Drug reaction with eosinophilia and systemic symptoms (550)
Pyrexia (517)
Nausea (488)
Paradoxical drug reaction (433)
Off label use (406)
Drug resistance (367)
Hepatotoxicity (349)
Headache (324)
What Other Drugs Cause Pancytopenia?
METHOTREXATE (5,377)
CYCLOPHOSPHAMIDE (3,351)
CARBOPLATIN (2,910)
RITUXIMAB (2,400)
LENALIDOMIDE (2,259)
DOXORUBICIN (2,212)
VINCRISTINE (2,180)
ETOPOSIDE (2,129)
DEXAMETHASONE (2,053)
PREDNISONE (1,743)
Which ISONIAZID Alternatives Have Lower Pancytopenia Risk?
ISONIAZID vs ISONIAZID\PYRAZINAMIDE\RIFAMPIN
ISONIAZID vs ISONIAZID\PYRIDOXINE\SULFAMETHOXAZOLE\TRIMETHOPRIM
ISONIAZID vs ISONIAZID\RIFAMPIN
ISONIAZID vs ISOPROPANOLAMINE
ISONIAZID vs ISOPROPYL ALCOHOL