Does IVACAFTOR Cause Hypersensitivity? 14 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 14 reports of Hypersensitivity have been filed in association with IVACAFTOR (Kalydeco). This represents 0.2% of all adverse event reports for IVACAFTOR.
14
Reports of Hypersensitivity with IVACAFTOR
0.2%
of all IVACAFTOR reports
0
Deaths
5
Hospitalizations
How Dangerous Is Hypersensitivity From IVACAFTOR?
Of the 14 reports, 5 (35.7%) required hospitalization, and 1 (7.1%) were considered life-threatening.
Is Hypersensitivity Listed in the Official Label?
Yes, Hypersensitivity is listed as a known adverse reaction in the official FDA drug label for IVACAFTOR.
What Other Side Effects Does IVACAFTOR Cause?
Hospitalisation (1,209)
Infective pulmonary exacerbation of cystic fibrosis (550)
Infection (227)
Malaise (226)
Lower respiratory tract infection (224)
Pneumonia (215)
Death (203)
Cough (180)
Cystic fibrosis (167)
Headache (163)
What Other Drugs Cause Hypersensitivity?
ETANERCEPT (10,846)
ADALIMUMAB (10,641)
METHOTREXATE (9,799)
TOCILIZUMAB (9,076)
ABATACEPT (8,945)
INFLIXIMAB (8,519)
RITUXIMAB (8,408)
ADAPALENE (8,356)
LEFLUNOMIDE (7,926)
CERTOLIZUMAB PEGOL (7,353)
Which IVACAFTOR Alternatives Have Lower Hypersensitivity Risk?
IVACAFTOR vs IVACAFTOR\LUMACAFTOR
IVACAFTOR vs IVACAFTOR\TEZACAFTOR
IVACAFTOR vs IVERMECTIN
IVACAFTOR vs IVOSIDENIB
IVACAFTOR vs IXABEPILONE