Does LAMOTRIGINE Cause Cholestasis? 107 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 107 reports of Cholestasis have been filed in association with LAMOTRIGINE (Lamotrigine ER). This represents 0.2% of all adverse event reports for LAMOTRIGINE.
107
Reports of Cholestasis with LAMOTRIGINE
0.2%
of all LAMOTRIGINE reports
0
Deaths
53
Hospitalizations
How Dangerous Is Cholestasis From LAMOTRIGINE?
Of the 107 reports, 53 (49.5%) required hospitalization, and 5 (4.7%) were considered life-threatening.
Is Cholestasis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LAMOTRIGINE. However, 107 reports have been filed with the FAERS database.
What Other Side Effects Does LAMOTRIGINE Cause?
Drug ineffective (5,175)
Seizure (3,459)
Toxicity to various agents (3,256)
Rash (3,249)
Foetal exposure during pregnancy (2,985)
Off label use (2,625)
Completed suicide (2,433)
Drug reaction with eosinophilia and systemic symptoms (2,235)
Dizziness (2,170)
Pyrexia (1,967)
What Other Drugs Cause Cholestasis?
ACETAMINOPHEN (1,269)
ATORVASTATIN (898)
PANTOPRAZOLE (535)
METHOTREXATE (507)
AMOXICILLIN\CLAVULANATE (480)
SULFAMETHOXAZOLE\TRIMETHOPRIM (462)
ENOXAPARIN (404)
PIPERACILLIN\TAZOBACTAM (394)
ESOMEPRAZOLE (363)
NIVOLUMAB (342)
Which LAMOTRIGINE Alternatives Have Lower Cholestasis Risk?
LAMOTRIGINE vs LANADELUMAB
LAMOTRIGINE vs LANADELUMAB-FLYO
LAMOTRIGINE vs LANREOTIDE
LAMOTRIGINE vs LANSOPRAZOLE
LAMOTRIGINE vs LANTHANUM