Does LAMOTRIGINE Cause Serotonin syndrome? 506 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 506 reports of Serotonin syndrome have been filed in association with LAMOTRIGINE (Lamotrigine ER). This represents 1.1% of all adverse event reports for LAMOTRIGINE.
506
Reports of Serotonin syndrome with LAMOTRIGINE
1.1%
of all LAMOTRIGINE reports
24
Deaths
393
Hospitalizations
How Dangerous Is Serotonin syndrome From LAMOTRIGINE?
Of the 506 reports, 24 (4.7%) resulted in death, 393 (77.7%) required hospitalization, and 122 (24.1%) were considered life-threatening.
Is Serotonin syndrome Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LAMOTRIGINE. However, 506 reports have been filed with the FAERS database.
What Other Side Effects Does LAMOTRIGINE Cause?
Drug ineffective (5,175)
Seizure (3,459)
Toxicity to various agents (3,256)
Rash (3,249)
Foetal exposure during pregnancy (2,985)
Off label use (2,625)
Completed suicide (2,433)
Drug reaction with eosinophilia and systemic symptoms (2,235)
Dizziness (2,170)
Pyrexia (1,967)
What Other Drugs Cause Serotonin syndrome?
VENLAFAXINE (1,632)
SERTRALINE (1,563)
FLUOXETINE (1,457)
DULOXETINE (1,352)
TRAMADOL (1,229)
BUPROPION (1,058)
ESCITALOPRAM OXALATE (1,051)
QUETIAPINE (947)
TRAZODONE (831)
FENTANYL (778)
Which LAMOTRIGINE Alternatives Have Lower Serotonin syndrome Risk?
LAMOTRIGINE vs LANADELUMAB
LAMOTRIGINE vs LANADELUMAB-FLYO
LAMOTRIGINE vs LANREOTIDE
LAMOTRIGINE vs LANSOPRAZOLE
LAMOTRIGINE vs LANTHANUM