Does LAMOTRIGINE Cause Spina bifida? 142 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 142 reports of Spina bifida have been filed in association with LAMOTRIGINE (Lamotrigine ER). This represents 0.3% of all adverse event reports for LAMOTRIGINE.
142
Reports of Spina bifida with LAMOTRIGINE
0.3%
of all LAMOTRIGINE reports
32
Deaths
7
Hospitalizations
How Dangerous Is Spina bifida From LAMOTRIGINE?
Of the 142 reports, 32 (22.5%) resulted in death, 7 (4.9%) required hospitalization.
Is Spina bifida Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LAMOTRIGINE. However, 142 reports have been filed with the FAERS database.
What Other Side Effects Does LAMOTRIGINE Cause?
Drug ineffective (5,175)
Seizure (3,459)
Toxicity to various agents (3,256)
Rash (3,249)
Foetal exposure during pregnancy (2,985)
Off label use (2,625)
Completed suicide (2,433)
Drug reaction with eosinophilia and systemic symptoms (2,235)
Dizziness (2,170)
Pyrexia (1,967)
What Other Drugs Cause Spina bifida?
OXYCODONE (268)
ACETAMINOPHEN\OXYCODONE (200)
ACETAMINOPHEN\HYDROCODONE (188)
HYDROMORPHONE (174)
MORPHINE (159)
TRAMADOL (136)
BUPRENORPHINE (107)
VALPROIC ACID (101)
HYDROCODONE (93)
LEVETIRACETAM (91)
Which LAMOTRIGINE Alternatives Have Lower Spina bifida Risk?
LAMOTRIGINE vs LANADELUMAB
LAMOTRIGINE vs LANADELUMAB-FLYO
LAMOTRIGINE vs LANREOTIDE
LAMOTRIGINE vs LANSOPRAZOLE
LAMOTRIGINE vs LANTHANUM