Does VALPROIC ACID Cause Spina bifida? 101 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 101 reports of Spina bifida have been filed in association with VALPROIC ACID (Valproic Acid). This represents 0.5% of all adverse event reports for VALPROIC ACID.
101
Reports of Spina bifida with VALPROIC ACID
0.5%
of all VALPROIC ACID reports
24
Deaths
5
Hospitalizations
How Dangerous Is Spina bifida From VALPROIC ACID?
Of the 101 reports, 24 (23.8%) resulted in death, 5 (5.0%) required hospitalization.
Is Spina bifida Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for VALPROIC ACID. However, 101 reports have been filed with the FAERS database.
What Other Side Effects Does VALPROIC ACID Cause?
Drug ineffective (3,511)
Drug interaction (1,542)
Toxicity to various agents (1,517)
Off label use (1,503)
Seizure (1,335)
Foetal exposure during pregnancy (1,046)
Somnolence (831)
Completed suicide (723)
Overdose (691)
Condition aggravated (673)
What Other Drugs Cause Spina bifida?
OXYCODONE (268)
ACETAMINOPHEN\OXYCODONE (200)
ACETAMINOPHEN\HYDROCODONE (188)
HYDROMORPHONE (174)
MORPHINE (159)
LAMOTRIGINE (142)
TRAMADOL (136)
BUPRENORPHINE (107)
HYDROCODONE (93)
LEVETIRACETAM (91)
Which VALPROIC ACID Alternatives Have Lower Spina bifida Risk?
VALPROIC ACID vs VALPROMIDE
VALPROIC ACID vs VALSARTAN
VALPROIC ACID vs VALTREX
VALPROIC ACID vs VAMOROLONE
VALPROIC ACID vs VANCOMYCIN