LAPATINIB for Disease progression: Side Effects & Safety Data
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There are 13 adverse event reports in the FDA FAERS database where LAPATINIB was used for Disease progression.
Most Reported Side Effects for LAPATINIB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Diarrhoea | 382 | 19.3% | 35 | 131 |
| Disease progression | 227 | 11.5% | 37 | 21 |
| Palmar-plantar erythrodysaesthesia syndrome | 182 | 9.2% | 18 | 24 |
| Malignant neoplasm progression | 173 | 8.7% | 41 | 21 |
| Nausea | 161 | 8.1% | 17 | 67 |
| Metastases to central nervous system | 160 | 8.1% | 32 | 32 |
| Neutropenia | 160 | 8.1% | 11 | 27 |
| Vomiting | 155 | 7.8% | 16 | 67 |
| Asthenia | 148 | 7.5% | 19 | 38 |
| Fatigue | 139 | 7.0% | 13 | 50 |
| Off label use | 118 | 6.0% | 12 | 42 |
| Rash | 108 | 5.5% | 8 | 18 |
| Thrombocytopenia | 102 | 5.1% | 8 | 20 |
| Metastases to lymph nodes | 95 | 4.8% | 3 | 29 |
| Metastases to lung | 92 | 4.6% | 8 | 10 |
Other Indications for LAPATINIB
Breast cancer (447)
Breast cancer metastatic (434)
Her2 positive breast cancer (241)
Product used for unknown indication (233)
Her-2 positive breast cancer (151)
Invasive ductal breast carcinoma (113)
Breast cancer female (37)
Neoplasm malignant (33)
Metastases to central nervous system (30)
Colorectal cancer metastatic (25)
Other Drugs Used for Disease progression
CAPECITABINE (57)
DEXAMETHASONE (53)
CYCLOPHOSPHAMIDE (52)
RITUXIMAB (52)
IRINOTECAN (50)
CARBOPLATIN (48)
IFOSFAMIDE (44)
CISPLATIN (41)
ETOPOSIDE (39)
PREDNISONE (39)