Does LAPATINIB Cause Onycholysis? 12 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 12 reports of Onycholysis have been filed in association with LAPATINIB. This represents 0.6% of all adverse event reports for LAPATINIB.
12
Reports of Onycholysis with LAPATINIB
0.6%
of all LAPATINIB reports
1
Deaths
0
Hospitalizations
How Dangerous Is Onycholysis From LAPATINIB?
Of the 12 reports, 1 (8.3%) resulted in death, and 2 (16.7%) were considered life-threatening.
Is Onycholysis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LAPATINIB. However, 12 reports have been filed with the FAERS database.
What Other Side Effects Does LAPATINIB Cause?
Diarrhoea (382)
Disease progression (227)
Palmar-plantar erythrodysaesthesia syndrome (182)
Malignant neoplasm progression (173)
Nausea (161)
Metastases to central nervous system (160)
Neutropenia (160)
Vomiting (155)
Asthenia (148)
Fatigue (139)
What Other Drugs Cause Onycholysis?
PACLITAXEL (173)
DOCETAXEL (130)
TRASTUZUMAB (109)
SECUKINUMAB (82)
ADALIMUMAB (77)
CAPECITABINE (73)
METHOTREXATE (67)
PERTUZUMAB (55)
ERDAFITINIB (44)
CARBOPLATIN (42)
Which LAPATINIB Alternatives Have Lower Onycholysis Risk?
LAPATINIB vs LAPATINIB DITOSYLATE
LAPATINIB vs LAPINE T-LYMPHOCYTE IMMUNE GLOBULIN
LAPATINIB vs LARONIDASE
LAPATINIB vs LAROTRECTINIB
LAPATINIB vs LASILIX