Does LEFLUNOMIDE Cause Adrenal insufficiency? 171 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 171 reports of Adrenal insufficiency have been filed in association with LEFLUNOMIDE (Leflunomide). This represents 0.3% of all adverse event reports for LEFLUNOMIDE.
171
Reports of Adrenal insufficiency with LEFLUNOMIDE
0.3%
of all LEFLUNOMIDE reports
26
Deaths
153
Hospitalizations
How Dangerous Is Adrenal insufficiency From LEFLUNOMIDE?
Of the 171 reports, 26 (15.2%) resulted in death, 153 (89.5%) required hospitalization, and 33 (19.3%) were considered life-threatening.
Is Adrenal insufficiency Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LEFLUNOMIDE. However, 171 reports have been filed with the FAERS database.
What Other Side Effects Does LEFLUNOMIDE Cause?
Drug ineffective (31,396)
Rheumatoid arthritis (20,886)
Pain (15,594)
Drug intolerance (14,142)
Joint swelling (13,026)
Fatigue (11,959)
Arthralgia (11,880)
Rash (11,239)
Contraindicated product administered (11,206)
Abdominal discomfort (10,333)
What Other Drugs Cause Adrenal insufficiency?
NIVOLUMAB (1,285)
PEMBROLIZUMAB (1,270)
PREDNISONE (1,105)
IPILIMUMAB (851)
METHOTREXATE (644)
ADALIMUMAB (554)
ETANERCEPT (546)
TOCILIZUMAB (541)
HYDROXYCHLOROQUINE (517)
INFLIXIMAB (509)
Which LEFLUNOMIDE Alternatives Have Lower Adrenal insufficiency Risk?
LEFLUNOMIDE vs LEMBOREXANT
LEFLUNOMIDE vs LENACAPAVIR
LEFLUNOMIDE vs LENALIDOMIDE
LEFLUNOMIDE vs LENIOLISIB
LEFLUNOMIDE vs LENOGRASTIM