Does LEFLUNOMIDE Cause Skin necrosis? 525 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 525 reports of Skin necrosis have been filed in association with LEFLUNOMIDE (Leflunomide). This represents 0.9% of all adverse event reports for LEFLUNOMIDE.
525
Reports of Skin necrosis with LEFLUNOMIDE
0.9%
of all LEFLUNOMIDE reports
6
Deaths
502
Hospitalizations
How Dangerous Is Skin necrosis From LEFLUNOMIDE?
Of the 525 reports, 6 (1.1%) resulted in death, 502 (95.6%) required hospitalization, and 21 (4.0%) were considered life-threatening.
Is Skin necrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LEFLUNOMIDE. However, 525 reports have been filed with the FAERS database.
What Other Side Effects Does LEFLUNOMIDE Cause?
Drug ineffective (31,396)
Rheumatoid arthritis (20,886)
Pain (15,594)
Drug intolerance (14,142)
Joint swelling (13,026)
Fatigue (11,959)
Arthralgia (11,880)
Rash (11,239)
Contraindicated product administered (11,206)
Abdominal discomfort (10,333)
What Other Drugs Cause Skin necrosis?
METHOTREXATE (620)
ADALIMUMAB (576)
RITUXIMAB (565)
TOCILIZUMAB (530)
ABATACEPT (528)
ETANERCEPT (493)
INFLIXIMAB (491)
HYDROXYCHLOROQUINE (482)
CODEINE (481)
SULFASALAZINE (475)
Which LEFLUNOMIDE Alternatives Have Lower Skin necrosis Risk?
LEFLUNOMIDE vs LEMBOREXANT
LEFLUNOMIDE vs LENACAPAVIR
LEFLUNOMIDE vs LENALIDOMIDE
LEFLUNOMIDE vs LENIOLISIB
LEFLUNOMIDE vs LENOGRASTIM