Does LETROZOLE Cause Hepatomegaly? 64 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 64 reports of Hepatomegaly have been filed in association with LETROZOLE (Letrozole). This represents 0.2% of all adverse event reports for LETROZOLE.
64
Reports of Hepatomegaly with LETROZOLE
0.2%
of all LETROZOLE reports
21
Deaths
32
Hospitalizations
How Dangerous Is Hepatomegaly From LETROZOLE?
Of the 64 reports, 21 (32.8%) resulted in death, 32 (50.0%) required hospitalization, and 14 (21.9%) were considered life-threatening.
Is Hepatomegaly Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LETROZOLE. However, 64 reports have been filed with the FAERS database.
What Other Side Effects Does LETROZOLE Cause?
Neutropenia (3,683)
Fatigue (3,568)
Malignant neoplasm progression (3,445)
Nausea (2,894)
Arthralgia (2,318)
Diarrhoea (2,282)
Metastases to bone (1,735)
Dyspnoea (1,621)
Asthenia (1,589)
Vomiting (1,560)
What Other Drugs Cause Hepatomegaly?
METHOTREXATE (276)
ADALIMUMAB (225)
RUXOLITINIB (213)
CYCLOPHOSPHAMIDE (170)
VINCRISTINE (136)
ACETAMINOPHEN (126)
RITUXIMAB (115)
DEXAMETHASONE (104)
PREDNISONE (101)
SECUKINUMAB (90)
Which LETROZOLE Alternatives Have Lower Hepatomegaly Risk?
LETROZOLE vs LETROZOLE\RIBOCICLIB
LETROZOLE vs LEUCOVORIN
LETROZOLE vs LEUCOVORIN\LEUCOVORIN
LETROZOLE vs LEUPROLIDE
LETROZOLE vs LEVALBUTEROL