Hepatomegaly: Which Medications Cause It? (5,773 Reports Across 510 Drugs)
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Hepatomegaly has been reported as an adverse event with 510 different drugs in the FDA's FAERS database, with 5,773 total reports. 855 of these reports resulted in death.The drugs most commonly associated with Hepatomegaly are METHOTREXATE, ADALIMUMAB, and RUXOLITINIB.
5,773
Total Reports
510
Drugs Involved
855
Deaths
2,841
Hospitalizations
45.9 yrs
Average Patient Age
58.1% / 41.9%
Female / Male
Which Drugs Cause Hepatomegaly Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| METHOTREXATE | 276 | 0.1% | 38 | 127 | 12 |
| ADALIMUMAB | 225 | 0.1% | 19 | 107 | 10 |
| RUXOLITINIB | 213 | 0.3% | 30 | 102 | 13 |
| CYCLOPHOSPHAMIDE | 170 | 0.1% | 55 | 95 | 31 |
| VINCRISTINE | 136 | 0.2% | 27 | 81 | 15 |
| ACETAMINOPHEN | 126 | 0.1% | 25 | 80 | 14 |
| RITUXIMAB | 115 | 0.1% | 22 | 57 | 12 |
| DEXAMETHASONE | 104 | 0.1% | 30 | 63 | 19 |
| PREDNISONE | 101 | 0.1% | 16 | 54 | 0 |
| SECUKINUMAB | 90 | 0.1% | 4 | 39 | 1 |
| OCTREOTIDE | 89 | 0.4% | 17 | 54 | 15 |
| ATORVASTATIN | 88 | 0.1% | 3 | 45 | 18 |
| CYTARABINE | 88 | 0.2% | 29 | 63 | 14 |
| DOXORUBICIN | 80 | 0.1% | 17 | 45 | 15 |
| ETANERCEPT | 77 | 0.0% | 0 | 17 | 1 |
| PEGASPARGASE | 77 | 0.7% | 16 | 54 | 10 |
| METFORMIN | 76 | 0.1% | 2 | 33 | 5 |
| PREDNISOLONE | 76 | 0.1% | 19 | 42 | 12 |
| TACROLIMUS | 73 | 0.1% | 24 | 60 | 19 |
| RIBOCICLIB | 72 | 0.3% | 20 | 26 | 10 |