Does LEUCOVORIN Cause Cholestasis? 101 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 101 reports of Cholestasis have been filed in association with LEUCOVORIN (LEUCOVORIN CALCIUM). This represents 0.4% of all adverse event reports for LEUCOVORIN.
101
Reports of Cholestasis with LEUCOVORIN
0.4%
of all LEUCOVORIN reports
21
Deaths
57
Hospitalizations
How Dangerous Is Cholestasis From LEUCOVORIN?
Of the 101 reports, 21 (20.8%) resulted in death, 57 (56.4%) required hospitalization.
Is Cholestasis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LEUCOVORIN. However, 101 reports have been filed with the FAERS database.
What Other Side Effects Does LEUCOVORIN Cause?
Diarrhoea (2,594)
Neutropenia (2,291)
Nausea (1,977)
Neuropathy peripheral (1,557)
Disease progression (1,456)
Fatigue (1,443)
Vomiting (1,441)
Off label use (1,390)
Thrombocytopenia (1,181)
Pyrexia (1,148)
What Other Drugs Cause Cholestasis?
ACETAMINOPHEN (1,269)
ATORVASTATIN (898)
PANTOPRAZOLE (535)
METHOTREXATE (507)
AMOXICILLIN\CLAVULANATE (480)
SULFAMETHOXAZOLE\TRIMETHOPRIM (462)
ENOXAPARIN (404)
PIPERACILLIN\TAZOBACTAM (394)
ESOMEPRAZOLE (363)
NIVOLUMAB (342)
Which LEUCOVORIN Alternatives Have Lower Cholestasis Risk?
LEUCOVORIN vs LEUCOVORIN\LEUCOVORIN
LEUCOVORIN vs LEUPROLIDE
LEUCOVORIN vs LEVALBUTEROL
LEUCOVORIN vs LEVAMISOLE
LEUCOVORIN vs LEVAQUIN