Does LORLATINIB Cause Constipation? 68 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 68 reports of Constipation have been filed in association with LORLATINIB (Lorbrena). This represents 1.2% of all adverse event reports for LORLATINIB.
68
Reports of Constipation with LORLATINIB
1.2%
of all LORLATINIB reports
11
Deaths
24
Hospitalizations
How Dangerous Is Constipation From LORLATINIB?
Of the 68 reports, 11 (16.2%) resulted in death, 24 (35.3%) required hospitalization, and 1 (1.5%) were considered life-threatening.
Is Constipation Listed in the Official Label?
Yes, Constipation is listed as a known adverse reaction in the official FDA drug label for LORLATINIB.
What Other Side Effects Does LORLATINIB Cause?
Death (1,050)
Neoplasm progression (633)
Off label use (394)
Weight increased (306)
Hallucination (290)
Blood cholesterol increased (281)
Dyspnoea (223)
Oedema peripheral (198)
Oedema (195)
Fatigue (188)
What Other Drugs Cause Constipation?
LENALIDOMIDE (9,635)
NIRAPARIB (4,128)
ADALIMUMAB (4,063)
SEMAGLUTIDE (4,036)
TIRZEPATIDE (3,417)
ERENUMAB-AOOE (3,104)
MORPHINE (2,979)
OXYCODONE (2,747)
PALBOCICLIB (2,705)
POMALIDOMIDE (2,374)
Which LORLATINIB Alternatives Have Lower Constipation Risk?
LORLATINIB vs LORMETAZEPAM
LORLATINIB vs LORNOXICAM
LORLATINIB vs LOSARTAN
LORLATINIB vs LOSARTAN\LOSARTAN
LORLATINIB vs LOTEPREDNOL ETABONATE