Does MERCAPTOPURINE Cause Cholestasis? 104 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 104 reports of Cholestasis have been filed in association with MERCAPTOPURINE (Mercaptopurine). This represents 0.9% of all adverse event reports for MERCAPTOPURINE.
104
Reports of Cholestasis with MERCAPTOPURINE
0.9%
of all MERCAPTOPURINE reports
2
Deaths
47
Hospitalizations
How Dangerous Is Cholestasis From MERCAPTOPURINE?
Of the 104 reports, 2 (1.9%) resulted in death, 47 (45.2%) required hospitalization, and 10 (9.6%) were considered life-threatening.
Is Cholestasis Listed in the Official Label?
Yes, Cholestasis is listed as a known adverse reaction in the official FDA drug label for MERCAPTOPURINE.
What Other Side Effects Does MERCAPTOPURINE Cause?
Febrile neutropenia (1,853)
Off label use (893)
Pyrexia (855)
Drug ineffective (721)
Vomiting (488)
Neutropenia (485)
Nausea (418)
Pneumonia (394)
Pancytopenia (392)
Sepsis (389)
What Other Drugs Cause Cholestasis?
ACETAMINOPHEN (1,269)
ATORVASTATIN (898)
PANTOPRAZOLE (535)
METHOTREXATE (507)
AMOXICILLIN\CLAVULANATE (480)
SULFAMETHOXAZOLE\TRIMETHOPRIM (462)
ENOXAPARIN (404)
PIPERACILLIN\TAZOBACTAM (394)
ESOMEPRAZOLE (363)
NIVOLUMAB (342)
Which MERCAPTOPURINE Alternatives Have Lower Cholestasis Risk?
MERCAPTOPURINE vs MEROPENEM
MERCAPTOPURINE vs MEROPENEM ANHYDROUS
MERCAPTOPURINE vs MESALAMINE
MERCAPTOPURINE vs MESNA
MERCAPTOPURINE vs METAMIZOLE