Does MERCAPTOPURINE Cause Clostridium difficile colitis? 261 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 261 reports of Clostridium difficile colitis have been filed in association with MERCAPTOPURINE (Mercaptopurine). This represents 2.3% of all adverse event reports for MERCAPTOPURINE.
261
Reports of Clostridium difficile colitis with MERCAPTOPURINE
2.3%
of all MERCAPTOPURINE reports
211
Deaths
50
Hospitalizations
How Dangerous Is Clostridium difficile colitis From MERCAPTOPURINE?
Of the 261 reports, 211 (80.8%) resulted in death, 50 (19.2%) required hospitalization, and 5 (1.9%) were considered life-threatening.
Is Clostridium difficile colitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MERCAPTOPURINE. However, 261 reports have been filed with the FAERS database.
What Other Side Effects Does MERCAPTOPURINE Cause?
Febrile neutropenia (1,853)
Off label use (893)
Pyrexia (855)
Drug ineffective (721)
Vomiting (488)
Neutropenia (485)
Nausea (418)
Pneumonia (394)
Pancytopenia (392)
Sepsis (389)
What Other Drugs Cause Clostridium difficile colitis?
CYCLOPHOSPHAMIDE (717)
PREDNISONE (619)
DEXAMETHASONE (575)
METHOTREXATE (562)
ETOPOSIDE (503)
CYTARABINE (489)
VINCRISTINE (482)
LENALIDOMIDE (388)
METHYLPREDNISOLONE (385)
CIPROFLOXACIN (378)
Which MERCAPTOPURINE Alternatives Have Lower Clostridium difficile colitis Risk?
MERCAPTOPURINE vs MEROPENEM
MERCAPTOPURINE vs MEROPENEM ANHYDROUS
MERCAPTOPURINE vs MESALAMINE
MERCAPTOPURINE vs MESNA
MERCAPTOPURINE vs METAMIZOLE