Does MESNA Cause Neutropenia? 238 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 238 reports of Neutropenia have been filed in association with MESNA (mesna). This represents 4.9% of all adverse event reports for MESNA.
238
Reports of Neutropenia with MESNA
4.9%
of all MESNA reports
36
Deaths
96
Hospitalizations
How Dangerous Is Neutropenia From MESNA?
Of the 238 reports, 36 (15.1%) resulted in death, 96 (40.3%) required hospitalization, and 24 (10.1%) were considered life-threatening.
Is Neutropenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MESNA. However, 238 reports have been filed with the FAERS database.
What Other Side Effects Does MESNA Cause?
Febrile neutropenia (707)
Pyrexia (352)
Off label use (299)
Cystitis haemorrhagic (294)
Disease progression (273)
Encephalopathy (226)
Vomiting (200)
Death (184)
Pancytopenia (179)
Diarrhoea (177)
What Other Drugs Cause Neutropenia?
CLOZAPINE (18,981)
CYCLOPHOSPHAMIDE (7,352)
LENALIDOMIDE (6,909)
RITUXIMAB (6,607)
PALBOCICLIB (6,423)
DEXAMETHASONE (6,050)
DOXORUBICIN (5,891)
CARBOPLATIN (5,314)
VINCRISTINE (4,982)
PACLITAXEL (4,553)
Which MESNA Alternatives Have Lower Neutropenia Risk?
MESNA vs METAMIZOLE
MESNA vs METARAMINOL
MESNA vs METAXALONE
MESNA vs METFORMIN
MESNA vs METFORMIN\PIOGLITAZONE