Does MESNA Cause Pancytopenia? 179 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 179 reports of Pancytopenia have been filed in association with MESNA (mesna). This represents 3.7% of all adverse event reports for MESNA.
179
Reports of Pancytopenia with MESNA
3.7%
of all MESNA reports
20
Deaths
96
Hospitalizations
How Dangerous Is Pancytopenia From MESNA?
Of the 179 reports, 20 (11.2%) resulted in death, 96 (53.6%) required hospitalization, and 14 (7.8%) were considered life-threatening.
Is Pancytopenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MESNA. However, 179 reports have been filed with the FAERS database.
What Other Side Effects Does MESNA Cause?
Febrile neutropenia (707)
Pyrexia (352)
Off label use (299)
Cystitis haemorrhagic (294)
Disease progression (273)
Neutropenia (238)
Encephalopathy (226)
Vomiting (200)
Death (184)
Diarrhoea (177)
What Other Drugs Cause Pancytopenia?
METHOTREXATE (5,377)
CYCLOPHOSPHAMIDE (3,351)
CARBOPLATIN (2,910)
RITUXIMAB (2,400)
LENALIDOMIDE (2,259)
DOXORUBICIN (2,212)
VINCRISTINE (2,180)
ETOPOSIDE (2,129)
DEXAMETHASONE (2,053)
PREDNISONE (1,743)
Which MESNA Alternatives Have Lower Pancytopenia Risk?
MESNA vs METAMIZOLE
MESNA vs METARAMINOL
MESNA vs METAXALONE
MESNA vs METFORMIN
MESNA vs METFORMIN\PIOGLITAZONE