Does MESNA Cause Encephalopathy? 226 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 226 reports of Encephalopathy have been filed in association with MESNA (mesna). This represents 4.6% of all adverse event reports for MESNA.
226
Reports of Encephalopathy with MESNA
4.6%
of all MESNA reports
27
Deaths
148
Hospitalizations
How Dangerous Is Encephalopathy From MESNA?
Of the 226 reports, 27 (11.9%) resulted in death, 148 (65.5%) required hospitalization, and 10 (4.4%) were considered life-threatening.
Is Encephalopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MESNA. However, 226 reports have been filed with the FAERS database.
What Other Side Effects Does MESNA Cause?
Febrile neutropenia (707)
Pyrexia (352)
Off label use (299)
Cystitis haemorrhagic (294)
Disease progression (273)
Neutropenia (238)
Vomiting (200)
Death (184)
Pancytopenia (179)
Diarrhoea (177)
What Other Drugs Cause Encephalopathy?
BACLOFEN (845)
METHOTREXATE (775)
ACETAMINOPHEN (608)
IFOSFAMIDE (585)
CYCLOPHOSPHAMIDE (552)
TACROLIMUS (523)
PREDNISONE (489)
DEXAMETHASONE (428)
METFORMIN (418)
ETOPOSIDE (404)
Which MESNA Alternatives Have Lower Encephalopathy Risk?
MESNA vs METAMIZOLE
MESNA vs METARAMINOL
MESNA vs METAXALONE
MESNA vs METFORMIN
MESNA vs METFORMIN\PIOGLITAZONE