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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Does METHOTREXATE Cause Encephalopathy? 775 Reports in FDA Database

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According to the FDA Adverse Event Reporting System (FAERS), 775 reports of Encephalopathy have been filed in association with METHOTREXATE (Methotrexate). This represents 0.3% of all adverse event reports for METHOTREXATE.

775
Reports of Encephalopathy with METHOTREXATE
0.3%
of all METHOTREXATE reports
186
Deaths
463
Hospitalizations

How Dangerous Is Encephalopathy From METHOTREXATE?

Of the 775 reports, 186 (24.0%) resulted in death, 463 (59.7%) required hospitalization, and 162 (20.9%) were considered life-threatening.

Is Encephalopathy Listed in the Official Label?

Yes, Encephalopathy is listed as a known adverse reaction in the official FDA drug label for METHOTREXATE.

What Other Side Effects Does METHOTREXATE Cause?

Drug ineffective (70,142) Rheumatoid arthritis (29,254) Off label use (24,020) Pain (23,773) Drug intolerance (22,555) Arthralgia (21,831) Fatigue (19,885) Nausea (18,715) Joint swelling (17,657) Drug hypersensitivity (16,677)

What Other Drugs Cause Encephalopathy?

BACLOFEN (845) ACETAMINOPHEN (608) IFOSFAMIDE (585) CYCLOPHOSPHAMIDE (552) TACROLIMUS (523) PREDNISONE (489) DEXAMETHASONE (428) METFORMIN (418) ETOPOSIDE (404) CEFEPIME (376)

Which METHOTREXATE Alternatives Have Lower Encephalopathy Risk?

METHOTREXATE vs METHOXSALEN METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA METHOTREXATE vs METHYL ALCOHOL METHOTREXATE vs METHYLCOBALAMIN METHOTREXATE vs METHYLDOPA

Related Pages

METHOTREXATE Full Profile All Encephalopathy Reports All Drugs Causing Encephalopathy METHOTREXATE Demographics