Encephalopathy: Which Medications Cause It? (16,791 Reports Across 813 Drugs)
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Encephalopathy has been reported as an adverse event with 813 different drugs in the FDA's FAERS database, with 16,791 total reports. 3,312 of these reports resulted in death.The drugs most commonly associated with Encephalopathy are BACLOFEN, METHOTREXATE, and ACETAMINOPHEN.
16,791
Total Reports
813
Drugs Involved
3,312
Deaths
11,348
Hospitalizations
54.4 yrs
Average Patient Age
50.8% / 49.2%
Female / Male
Which Drugs Cause Encephalopathy Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| BACLOFEN | 845 | 3.3% | 19 | 326 | 47 |
| METHOTREXATE | 775 | 0.3% | 186 | 463 | 162 |
| ACETAMINOPHEN | 608 | 0.4% | 231 | 484 | 170 |
| IFOSFAMIDE | 585 | 3.4% | 72 | 287 | 54 |
| CYCLOPHOSPHAMIDE | 552 | 0.4% | 193 | 341 | 106 |
| TACROLIMUS | 523 | 0.6% | 196 | 388 | 177 |
| PREDNISONE | 489 | 0.3% | 183 | 392 | 204 |
| DEXAMETHASONE | 428 | 0.3% | 180 | 285 | 97 |
| METFORMIN | 418 | 0.5% | 71 | 312 | 157 |
| ETOPOSIDE | 404 | 0.8% | 92 | 239 | 43 |
| CEFEPIME | 376 | 6.8% | 63 | 254 | 77 |
| LEVETIRACETAM | 367 | 0.6% | 22 | 215 | 24 |
| RITUXIMAB | 358 | 0.2% | 143 | 223 | 72 |
| METHYLPREDNISOLONE | 327 | 0.5% | 149 | 234 | 99 |
| VINCRISTINE | 327 | 0.5% | 95 | 187 | 62 |
| METRONIDAZOLE | 324 | 1.4% | 46 | 174 | 48 |
| DOXORUBICIN | 306 | 0.4% | 82 | 176 | 49 |
| GABAPENTIN | 306 | 0.4% | 48 | 240 | 50 |
| QUETIAPINE | 304 | 0.4% | 84 | 243 | 84 |
| MYCOPHENOLATE MOFETIL | 303 | 0.4% | 160 | 226 | 125 |