Does METFORMIN Cause Encephalopathy? 418 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 418 reports of Encephalopathy have been filed in association with METFORMIN (Metformin Hydrochloride). This represents 0.5% of all adverse event reports for METFORMIN.
418
Reports of Encephalopathy with METFORMIN
0.5%
of all METFORMIN reports
71
Deaths
312
Hospitalizations
How Dangerous Is Encephalopathy From METFORMIN?
Of the 418 reports, 71 (17.0%) resulted in death, 312 (74.6%) required hospitalization, and 157 (37.6%) were considered life-threatening.
Is Encephalopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METFORMIN. However, 418 reports have been filed with the FAERS database.
What Other Side Effects Does METFORMIN Cause?
Lactic acidosis (16,316)
Acute kidney injury (11,361)
Diarrhoea (7,679)
Toxicity to various agents (5,669)
Metabolic acidosis (5,236)
Hypoglycaemia (5,047)
Drug ineffective (4,991)
Nausea (4,915)
Vomiting (4,624)
Blood glucose increased (4,038)
What Other Drugs Cause Encephalopathy?
BACLOFEN (845)
METHOTREXATE (775)
ACETAMINOPHEN (608)
IFOSFAMIDE (585)
CYCLOPHOSPHAMIDE (552)
TACROLIMUS (523)
PREDNISONE (489)
DEXAMETHASONE (428)
ETOPOSIDE (404)
CEFEPIME (376)
Which METFORMIN Alternatives Have Lower Encephalopathy Risk?
METFORMIN vs METFORMIN\PIOGLITAZONE
METFORMIN vs METFORMIN\ROSIGLITAZONE
METFORMIN vs METFORMIN\SAXAGLIPTIN
METFORMIN vs METFORMIN\SITAGLIPTIN
METFORMIN vs METFORMIN\VILDAGLIPTIN