Does METFORMIN Cause Hepatitis? 242 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 242 reports of Hepatitis have been filed in association with METFORMIN (Metformin Hydrochloride). This represents 0.3% of all adverse event reports for METFORMIN.
242
Reports of Hepatitis with METFORMIN
0.3%
of all METFORMIN reports
111
Deaths
185
Hospitalizations
How Dangerous Is Hepatitis From METFORMIN?
Of the 242 reports, 111 (45.9%) resulted in death, 185 (76.4%) required hospitalization, and 112 (46.3%) were considered life-threatening.
Is Hepatitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METFORMIN. However, 242 reports have been filed with the FAERS database.
What Other Side Effects Does METFORMIN Cause?
Lactic acidosis (16,316)
Acute kidney injury (11,361)
Diarrhoea (7,679)
Toxicity to various agents (5,669)
Metabolic acidosis (5,236)
Hypoglycaemia (5,047)
Drug ineffective (4,991)
Nausea (4,915)
Vomiting (4,624)
Blood glucose increased (4,038)
What Other Drugs Cause Hepatitis?
METHOTREXATE (1,835)
ACETAMINOPHEN (1,450)
TOCILIZUMAB (1,184)
HYDROXYCHLOROQUINE (1,133)
ADALIMUMAB (1,096)
RITUXIMAB (1,017)
ETANERCEPT (1,013)
LEFLUNOMIDE (997)
PEMBROLIZUMAB (935)
NIVOLUMAB (930)
Which METFORMIN Alternatives Have Lower Hepatitis Risk?
METFORMIN vs METFORMIN\PIOGLITAZONE
METFORMIN vs METFORMIN\ROSIGLITAZONE
METFORMIN vs METFORMIN\SAXAGLIPTIN
METFORMIN vs METFORMIN\SITAGLIPTIN
METFORMIN vs METFORMIN\VILDAGLIPTIN