Does METFORMIN Cause Hypothyroidism? 502 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 502 reports of Hypothyroidism have been filed in association with METFORMIN (Metformin Hydrochloride). This represents 0.6% of all adverse event reports for METFORMIN.
502
Reports of Hypothyroidism with METFORMIN
0.6%
of all METFORMIN reports
83
Deaths
195
Hospitalizations
How Dangerous Is Hypothyroidism From METFORMIN?
Of the 502 reports, 83 (16.5%) resulted in death, 195 (38.8%) required hospitalization, and 173 (34.5%) were considered life-threatening.
Is Hypothyroidism Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METFORMIN. However, 502 reports have been filed with the FAERS database.
What Other Side Effects Does METFORMIN Cause?
Lactic acidosis (16,316)
Acute kidney injury (11,361)
Diarrhoea (7,679)
Toxicity to various agents (5,669)
Metabolic acidosis (5,236)
Hypoglycaemia (5,047)
Drug ineffective (4,991)
Nausea (4,915)
Vomiting (4,624)
Blood glucose increased (4,038)
What Other Drugs Cause Hypothyroidism?
PEMBROLIZUMAB (2,326)
LEVOTHYROXINE (2,107)
NIVOLUMAB (1,939)
LENVATINIB (1,375)
ATEZOLIZUMAB (881)
ALBUTEROL (877)
CARBOPLATIN (830)
IPILIMUMAB (770)
AMIODARONE (764)
PREDNISONE (739)
Which METFORMIN Alternatives Have Lower Hypothyroidism Risk?
METFORMIN vs METFORMIN\PIOGLITAZONE
METFORMIN vs METFORMIN\ROSIGLITAZONE
METFORMIN vs METFORMIN\SAXAGLIPTIN
METFORMIN vs METFORMIN\SITAGLIPTIN
METFORMIN vs METFORMIN\VILDAGLIPTIN