Does METFORMIN Cause Synovitis? 350 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 350 reports of Synovitis have been filed in association with METFORMIN (Metformin Hydrochloride). This represents 0.4% of all adverse event reports for METFORMIN.
350
Reports of Synovitis with METFORMIN
0.4%
of all METFORMIN reports
170
Deaths
237
Hospitalizations
How Dangerous Is Synovitis From METFORMIN?
Of the 350 reports, 170 (48.6%) resulted in death, 237 (67.7%) required hospitalization, and 183 (52.3%) were considered life-threatening.
Is Synovitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METFORMIN. However, 350 reports have been filed with the FAERS database.
What Other Side Effects Does METFORMIN Cause?
Lactic acidosis (16,316)
Acute kidney injury (11,361)
Diarrhoea (7,679)
Toxicity to various agents (5,669)
Metabolic acidosis (5,236)
Hypoglycaemia (5,047)
Drug ineffective (4,991)
Nausea (4,915)
Vomiting (4,624)
Blood glucose increased (4,038)
What Other Drugs Cause Synovitis?
METHOTREXATE (11,451)
ADALIMUMAB (9,965)
ABATACEPT (9,783)
ETANERCEPT (9,599)
TOCILIZUMAB (9,428)
HYDROXYCHLOROQUINE (9,123)
LEFLUNOMIDE (8,889)
RITUXIMAB (7,956)
INFLIXIMAB (7,856)
SULFASALAZINE (7,566)
Which METFORMIN Alternatives Have Lower Synovitis Risk?
METFORMIN vs METFORMIN\PIOGLITAZONE
METFORMIN vs METFORMIN\ROSIGLITAZONE
METFORMIN vs METFORMIN\SAXAGLIPTIN
METFORMIN vs METFORMIN\SITAGLIPTIN
METFORMIN vs METFORMIN\VILDAGLIPTIN