Does METHYLENE BLUE Cause Serotonin syndrome? 260 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 260 reports of Serotonin syndrome have been filed in association with METHYLENE BLUE (Methylene blue). This represents 30.7% of all adverse event reports for METHYLENE BLUE.
260
Reports of Serotonin syndrome with METHYLENE BLUE
30.7%
of all METHYLENE BLUE reports
5
Deaths
215
Hospitalizations
How Dangerous Is Serotonin syndrome From METHYLENE BLUE?
Of the 260 reports, 5 (1.9%) resulted in death, 215 (82.7%) required hospitalization, and 97 (37.3%) were considered life-threatening.
Is Serotonin syndrome Listed in the Official Label?
Yes, Serotonin syndrome is listed as a known adverse reaction in the official FDA drug label for METHYLENE BLUE.
What Other Side Effects Does METHYLENE BLUE Cause?
Drug ineffective (222)
Hypotension (143)
Drug interaction (135)
Off label use (112)
Toxicity to various agents (93)
Overdose (69)
Intentional overdose (61)
Bradycardia (57)
Lactic acidosis (50)
Vasoplegia syndrome (50)
What Other Drugs Cause Serotonin syndrome?
VENLAFAXINE (1,632)
SERTRALINE (1,563)
FLUOXETINE (1,457)
DULOXETINE (1,352)
TRAMADOL (1,229)
BUPROPION (1,058)
ESCITALOPRAM OXALATE (1,051)
QUETIAPINE (947)
TRAZODONE (831)
FENTANYL (778)
Which METHYLENE BLUE Alternatives Have Lower Serotonin syndrome Risk?
METHYLENE BLUE vs METHYLENEDIOXYPYROVALERONE
METHYLENE BLUE vs METHYLERGONOVINE
METHYLENE BLUE vs METHYLNALTREXONE
METHYLENE BLUE vs METHYLPHENIDATE
METHYLENE BLUE vs METHYLPREDNISOLONE