METHYLNALTREXONE for Constipation: Side Effects & Safety Data
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There are 388 adverse event reports in the FDA FAERS database where METHYLNALTREXONE was used for Constipation.
Most Reported Side Effects for METHYLNALTREXONE
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Death | 214 | 25.9% | 214 | 4 |
| Drug ineffective | 148 | 17.9% | 3 | 16 |
| Constipation | 57 | 6.9% | 1 | 12 |
| Abdominal pain | 54 | 6.5% | 1 | 13 |
| Diarrhoea | 41 | 5.0% | 0 | 10 |
| Nausea | 35 | 4.2% | 1 | 4 |
| Abdominal pain upper | 33 | 4.0% | 0 | 5 |
| Off label use | 29 | 3.5% | 2 | 3 |
| Vomiting | 29 | 3.5% | 0 | 6 |
| Pain | 26 | 3.2% | 0 | 4 |
| Abdominal distension | 24 | 2.9% | 0 | 5 |
| Hospitalisation | 24 | 2.9% | 2 | 24 |
| Therapy interrupted | 21 | 2.5% | 2 | 6 |
| Headache | 20 | 2.4% | 0 | 2 |
| Hyperhidrosis | 20 | 2.4% | 0 | 3 |
Other Indications for METHYLNALTREXONE
Other Drugs Used for Constipation
POLYETHYLENE GLYCOL 3350 (9,960)
LINACLOTIDE (5,348)
NALOXEGOL OXALATE (1,418)
LACTULOSE (1,115)
BISACODYL (1,013)
POLYETHYLENE GLYCOL 3350\POTASSIUM\SODIUM BICARBONATE\SODIUM (709)
POLYETHYLENE GLYCOLS (667)
MAGNESIUM (648)
MAGNESIUM HYDROXIDE (635)
LUBIPROSTONE (563)