Does METHYLPHENIDATE Cause Serotonin syndrome? 177 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 177 reports of Serotonin syndrome have been filed in association with METHYLPHENIDATE (Methylphenidate Hydrochloride). This represents 0.6% of all adverse event reports for METHYLPHENIDATE.
177
Reports of Serotonin syndrome with METHYLPHENIDATE
0.6%
of all METHYLPHENIDATE reports
2
Deaths
98
Hospitalizations
How Dangerous Is Serotonin syndrome From METHYLPHENIDATE?
Of the 177 reports, 2 (1.1%) resulted in death, 98 (55.4%) required hospitalization, and 53 (29.9%) were considered life-threatening.
Is Serotonin syndrome Listed in the Official Label?
Yes, Serotonin syndrome is listed as a known adverse reaction in the official FDA drug label for METHYLPHENIDATE.
What Other Side Effects Does METHYLPHENIDATE Cause?
Drug ineffective (4,924)
Off label use (4,842)
No adverse event (4,197)
Product quality issue (1,728)
Disturbance in attention (1,414)
Product substitution issue (1,408)
Anxiety (1,356)
Drug dose omission (1,330)
Headache (1,255)
Wrong technique in product usage process (1,250)
What Other Drugs Cause Serotonin syndrome?
VENLAFAXINE (1,632)
SERTRALINE (1,563)
FLUOXETINE (1,457)
DULOXETINE (1,352)
TRAMADOL (1,229)
BUPROPION (1,058)
ESCITALOPRAM OXALATE (1,051)
QUETIAPINE (947)
TRAZODONE (831)
FENTANYL (778)
Which METHYLPHENIDATE Alternatives Have Lower Serotonin syndrome Risk?
METHYLPHENIDATE vs METHYLPREDNISOLONE
METHYLPHENIDATE vs METHYLPREDNISOLONE ACEPONATE
METHYLPHENIDATE vs METHYLPREDNISOLONE HEMISUCCINATE
METHYLPHENIDATE vs METILDIGOXIN
METHYLPHENIDATE vs METOCLOPRAMIDE