Does METHYLPREDNISOLONE Cause Hepatic necrosis? 55 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 55 reports of Hepatic necrosis have been filed in association with METHYLPREDNISOLONE (Medroloan II SUIK). This represents 0.1% of all adverse event reports for METHYLPREDNISOLONE.
55
Reports of Hepatic necrosis with METHYLPREDNISOLONE
0.1%
of all METHYLPREDNISOLONE reports
35
Deaths
42
Hospitalizations
How Dangerous Is Hepatic necrosis From METHYLPREDNISOLONE?
Of the 55 reports, 35 (63.6%) resulted in death, 42 (76.4%) required hospitalization, and 26 (47.3%) were considered life-threatening.
Is Hepatic necrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHYLPREDNISOLONE. However, 55 reports have been filed with the FAERS database.
What Other Side Effects Does METHYLPREDNISOLONE Cause?
Off label use (10,364)
Drug ineffective (9,959)
Product use in unapproved indication (4,115)
Condition aggravated (3,784)
Headache (3,419)
Fatigue (3,250)
Pyrexia (3,226)
Pain (3,165)
Nausea (3,105)
Pneumonia (3,006)
What Other Drugs Cause Hepatic necrosis?
ACETAMINOPHEN (216)
CYCLOPHOSPHAMIDE (83)
PREDNISONE (78)
VENLAFAXINE (69)
TACROLIMUS (67)
MYCOPHENOLATE MOFETIL (61)
METHOTREXATE (55)
SOMATROPIN (50)
DIMETHYL SULFONE (49)
ESTRADIOL (49)
Which METHYLPREDNISOLONE Alternatives Have Lower Hepatic necrosis Risk?
METHYLPREDNISOLONE vs METHYLPREDNISOLONE ACEPONATE
METHYLPREDNISOLONE vs METHYLPREDNISOLONE HEMISUCCINATE
METHYLPREDNISOLONE vs METILDIGOXIN
METHYLPREDNISOLONE vs METOCLOPRAMIDE
METHYLPREDNISOLONE vs METOLAZONE