Does TACROLIMUS Cause Hepatic necrosis? 67 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 67 reports of Hepatic necrosis have been filed in association with TACROLIMUS (Tacrolimus). This represents 0.1% of all adverse event reports for TACROLIMUS.
67
Reports of Hepatic necrosis with TACROLIMUS
0.1%
of all TACROLIMUS reports
46
Deaths
52
Hospitalizations
How Dangerous Is Hepatic necrosis From TACROLIMUS?
Of the 67 reports, 46 (68.7%) resulted in death, 52 (77.6%) required hospitalization, and 16 (23.9%) were considered life-threatening.
Is Hepatic necrosis Listed in the Official Label?
Yes, Hepatic necrosis is listed as a known adverse reaction in the official FDA drug label for TACROLIMUS.
What Other Side Effects Does TACROLIMUS Cause?
Off label use (8,718)
Drug ineffective (6,214)
Product use in unapproved indication (5,057)
Acute kidney injury (4,005)
Transplant rejection (3,526)
Cytomegalovirus infection (3,320)
Covid-19 (3,201)
Drug interaction (2,896)
Diarrhoea (2,854)
Toxicity to various agents (2,845)
What Other Drugs Cause Hepatic necrosis?
ACETAMINOPHEN (216)
CYCLOPHOSPHAMIDE (83)
PREDNISONE (78)
VENLAFAXINE (69)
MYCOPHENOLATE MOFETIL (61)
METHOTREXATE (55)
METHYLPREDNISOLONE (55)
SOMATROPIN (50)
DIMETHYL SULFONE (49)
ESTRADIOL (49)
Which TACROLIMUS Alternatives Have Lower Hepatic necrosis Risk?
TACROLIMUS vs TACROLIMUS\TACROLIMUS ANHYDROUS
TACROLIMUS vs TADALAFIL
TACROLIMUS vs TAFAMIDIS
TACROLIMUS vs TAFAMIDIS MEGLUMINE
TACROLIMUS vs TAFASITAMAB