Does MIDAZOLAM Cause Local anaesthetic systemic toxicity? 11 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 11 reports of Local anaesthetic systemic toxicity have been filed in association with MIDAZOLAM (Midazolam). This represents 0.1% of all adverse event reports for MIDAZOLAM.
11
Reports of Local anaesthetic systemic toxicity with MIDAZOLAM
0.1%
of all MIDAZOLAM reports
2
Deaths
8
Hospitalizations
How Dangerous Is Local anaesthetic systemic toxicity From MIDAZOLAM?
Of the 11 reports, 2 (18.2%) resulted in death, 8 (72.7%) required hospitalization, and 3 (27.3%) were considered life-threatening.
Is Local anaesthetic systemic toxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MIDAZOLAM. However, 11 reports have been filed with the FAERS database.
What Other Side Effects Does MIDAZOLAM Cause?
Drug ineffective (2,116)
Off label use (1,309)
Seizure (759)
Hypotension (695)
Toxicity to various agents (494)
Drug ineffective for unapproved indication (388)
Pyrexia (378)
Status epilepticus (369)
Product use in unapproved indication (356)
Cardiac arrest (350)
What Other Drugs Cause Local anaesthetic systemic toxicity?
LIDOCAINE (511)
BUPIVACAINE (188)
ROPIVACAINE (109)
EPINEPHRINE (59)
PROPOFOL (23)
EPINEPHRINE\LIDOCAINE (19)
FENTANYL (18)
KETAMINE (12)
MEPIVACAINE (11)
REMIFENTANIL (11)
Which MIDAZOLAM Alternatives Have Lower Local anaesthetic systemic toxicity Risk?
MIDAZOLAM vs MIDAZOLAM\MIDAZOLAM
MIDAZOLAM vs MIDODRINE
MIDAZOLAM vs MIDOMAFETAMINE
MIDAZOLAM vs MIDOSTAURIN
MIDAZOLAM vs MIFEPRISTONE