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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

All Drugs Associated with Local anaesthetic systemic toxicity

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28 drugs have been associated with Local anaesthetic systemic toxicity in FAERS reports.

Drug Reports Deaths Hosp. Life-Threat.
LIDOCAINE 511 22 364 250
BUPIVACAINE 188 6 118 99
ROPIVACAINE 109 8 73 42
EPINEPHRINE 59 1 42 25
PROPOFOL 23 4 20 16
EPINEPHRINE\LIDOCAINE 19 0 12 6
FENTANYL 18 0 11 9
KETAMINE 12 1 10 7
MEPIVACAINE 11 0 5 6
MIDAZOLAM 11 2 8 3
REMIFENTANIL 11 1 10 6
METOPROLOL 10 0 9 0
NOREPINEPHRINE 9 0 7 7
BUPROPION 8 0 7 0
LIDOCAINE ANHYDROUS 8 0 8 5
AMIODARONE 7 2 5 2
EGG PHOSPHOLIPIDS\SAFFLOWER OIL\SOYBEAN OIL 7 6 5 0
NITRIC 7 0 7 0
VASOPRESSIN 7 0 6 6
DIVALPROEX 6 0 6 0
LIDOCAINE\PRILOCAINE 6 1 5 3
PHENYLEPHRINE 6 0 5 5
ARTICAINE 5 1 4 4
BACLOFEN 5 0 5 2
BUPIVACAINE\BUPIVACAINE ANHYDROUS 5 0 4 4
DOBUTAMINE 5 0 4 4
ROCURONIUM 5 0 5 4
SODIUM BICARBONATE 5 2 4 0