Does MIDOSTAURIN Cause Cardiac failure? 33 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 33 reports of Cardiac failure have been filed in association with MIDOSTAURIN (RYDAPT). This represents 1.1% of all adverse event reports for MIDOSTAURIN.
33
Reports of Cardiac failure with MIDOSTAURIN
1.1%
of all MIDOSTAURIN reports
8
Deaths
23
Hospitalizations
How Dangerous Is Cardiac failure From MIDOSTAURIN?
Of the 33 reports, 8 (24.2%) resulted in death, 23 (69.7%) required hospitalization, and 3 (9.1%) were considered life-threatening.
Is Cardiac failure Listed in the Official Label?
Yes, Cardiac failure is listed as a known adverse reaction in the official FDA drug label for MIDOSTAURIN.
What Other Side Effects Does MIDOSTAURIN Cause?
Death (397)
Nausea (252)
Febrile neutropenia (223)
Diarrhoea (194)
Pyrexia (188)
Acute myeloid leukaemia recurrent (171)
Pancytopenia (152)
Vomiting (152)
Drug ineffective (151)
Thrombocytopenia (140)
What Other Drugs Cause Cardiac failure?
SACUBITRIL\VALSARTAN (4,504)
FUROSEMIDE (1,841)
APIXABAN (1,575)
CYCLOPHOSPHAMIDE (1,514)
DOXORUBICIN (1,367)
ADALIMUMAB (1,278)
DEXAMETHASONE (1,271)
TREPROSTINIL (1,168)
BISOPROLOL (1,159)
LENALIDOMIDE (1,115)
Which MIDOSTAURIN Alternatives Have Lower Cardiac failure Risk?
MIDOSTAURIN vs MIFEPRISTONE
MIDOSTAURIN vs MIGALASTAT
MIDOSTAURIN vs MIGLITOL
MIDOSTAURIN vs MIGLUSTAT
MIDOSTAURIN vs MILNACIPRAN