MITOTANE for Adjuvant therapy: Side Effects & Safety Data
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There are 18 adverse event reports in the FDA FAERS database where MITOTANE was used for Adjuvant therapy.
Most Reported Side Effects for MITOTANE
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Nausea | 210 | 20.8% | 6 | 37 |
| Fatigue | 205 | 20.3% | 10 | 42 |
| Off label use | 154 | 15.2% | 11 | 25 |
| Diarrhoea | 123 | 12.2% | 3 | 22 |
| Vomiting | 97 | 9.6% | 6 | 29 |
| Drug ineffective | 86 | 8.5% | 10 | 25 |
| Decreased appetite | 77 | 7.6% | 5 | 25 |
| Adrenal insufficiency | 76 | 7.5% | 2 | 18 |
| Dizziness | 76 | 7.5% | 2 | 12 |
| Asthenia | 70 | 6.9% | 3 | 24 |
| Malignant neoplasm progression | 61 | 6.0% | 15 | 14 |
| Neutropenia | 48 | 4.8% | 4 | 7 |
| Febrile neutropenia | 42 | 4.2% | 2 | 4 |
| Headache | 42 | 4.2% | 1 | 11 |
| Anaemia | 41 | 4.1% | 2 | 12 |
Other Indications for MITOTANE
Adrenocortical carcinoma (461)
Adrenal gland cancer (250)
Product used for unknown indication (88)
Metastases to lung (25)
Metastases to liver (23)
Cushing's syndrome (22)
Metastatic neoplasm (22)
Chemotherapy (10)
Neoplasm malignant (10)
Adrenal gland cancer metastatic (9)
Other Drugs Used for Adjuvant therapy
BREXPIPRAZOLE (2,296)
CYCLOPHOSPHAMIDE (236)
FLUOROURACIL (218)
EPIRUBICIN (206)
ARIPIPRAZOLE (171)
CAPECITABINE (120)
ZOLEDRONIC ACID (89)
OXALIPLATIN (75)
DOCETAXEL (65)
LETROZOLE (64)