MITOTANE for Metastases to liver: Side Effects & Safety Data
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There are 23 adverse event reports in the FDA FAERS database where MITOTANE was used for Metastases to liver.
Most Reported Side Effects for MITOTANE
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Nausea | 210 | 20.8% | 6 | 37 |
| Fatigue | 205 | 20.3% | 10 | 42 |
| Off label use | 154 | 15.2% | 11 | 25 |
| Diarrhoea | 123 | 12.2% | 3 | 22 |
| Vomiting | 97 | 9.6% | 6 | 29 |
| Drug ineffective | 86 | 8.5% | 10 | 25 |
| Decreased appetite | 77 | 7.6% | 5 | 25 |
| Adrenal insufficiency | 76 | 7.5% | 2 | 18 |
| Dizziness | 76 | 7.5% | 2 | 12 |
| Asthenia | 70 | 6.9% | 3 | 24 |
| Malignant neoplasm progression | 61 | 6.0% | 15 | 14 |
| Neutropenia | 48 | 4.8% | 4 | 7 |
| Febrile neutropenia | 42 | 4.2% | 2 | 4 |
| Headache | 42 | 4.2% | 1 | 11 |
| Anaemia | 41 | 4.1% | 2 | 12 |
Other Indications for MITOTANE
Adrenocortical carcinoma (461)
Adrenal gland cancer (250)
Product used for unknown indication (88)
Metastases to lung (25)
Cushing's syndrome (22)
Metastatic neoplasm (22)
Adjuvant therapy (18)
Chemotherapy (10)
Neoplasm malignant (10)
Adrenal gland cancer metastatic (9)
Other Drugs Used for Metastases to liver
OXALIPLATIN (1,219)
FLUOROURACIL (1,064)
BEVACIZUMAB (873)
CAPECITABINE (706)
LEUCOVORIN (655)
IRINOTECAN (622)
PANITUMUMAB (391)
PACLITAXEL (384)
CARBOPLATIN (302)
CABOZANTINIB S-MALATE (257)