MITOTANE for Adrenocortical carcinoma: Side Effects & Safety Data

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There are 461 adverse event reports in the FDA FAERS database where MITOTANE was used for Adrenocortical carcinoma.

Most Reported Side Effects for MITOTANE

Side Effect	Reports	%	Deaths	Hosp.
Nausea	210	20.8%	6	37
Fatigue	205	20.3%	10	42
Off label use	154	15.2%	11	25
Diarrhoea	123	12.2%	3	22
Vomiting	97	9.6%	6	29
Drug ineffective	86	8.5%	10	25
Decreased appetite	77	7.6%	5	25
Adrenal insufficiency	76	7.5%	2	18
Dizziness	76	7.5%	2	12
Asthenia	70	6.9%	3	24
Malignant neoplasm progression	61	6.0%	15	14
Neutropenia	48	4.8%	4	7
Febrile neutropenia	42	4.2%	2	4
Headache	42	4.2%	1	11
Anaemia	41	4.1%	2	12