Does MITOTANE Cause Hypothyroidism? 27 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 27 reports of Hypothyroidism have been filed in association with MITOTANE (Lysodren). This represents 2.7% of all adverse event reports for MITOTANE.
27
Reports of Hypothyroidism with MITOTANE
2.7%
of all MITOTANE reports
2
Deaths
6
Hospitalizations
How Dangerous Is Hypothyroidism From MITOTANE?
Of the 27 reports, 2 (7.4%) resulted in death, 6 (22.2%) required hospitalization, and 1 (3.7%) were considered life-threatening.
Is Hypothyroidism Listed in the Official Label?
Yes, Hypothyroidism is listed as a known adverse reaction in the official FDA drug label for MITOTANE.
What Other Side Effects Does MITOTANE Cause?
Nausea (210)
Fatigue (205)
Off label use (154)
Diarrhoea (123)
Vomiting (97)
Drug ineffective (86)
Decreased appetite (77)
Adrenal insufficiency (76)
Dizziness (76)
Asthenia (70)
What Other Drugs Cause Hypothyroidism?
PEMBROLIZUMAB (2,326)
LEVOTHYROXINE (2,107)
NIVOLUMAB (1,939)
LENVATINIB (1,375)
ATEZOLIZUMAB (881)
ALBUTEROL (877)
CARBOPLATIN (830)
IPILIMUMAB (770)
AMIODARONE (764)
PREDNISONE (739)
Which MITOTANE Alternatives Have Lower Hypothyroidism Risk?
MITOTANE vs MITOXANTRONE
MITOTANE vs MITRAGYNINE\HERBALS
MITOTANE vs MIZORIBINE
MITOTANE vs MOBOCERTINIB
MITOTANE vs MOCLOBEMIDE