Does MITOXANTRONE Cause Bone marrow failure? 99 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 99 reports of Bone marrow failure have been filed in association with MITOXANTRONE (mitoXANTRONE). This represents 2.4% of all adverse event reports for MITOXANTRONE.
99
Reports of Bone marrow failure with MITOXANTRONE
2.4%
of all MITOXANTRONE reports
34
Deaths
46
Hospitalizations
How Dangerous Is Bone marrow failure From MITOXANTRONE?
Of the 99 reports, 34 (34.3%) resulted in death, 46 (46.5%) required hospitalization, and 10 (10.1%) were considered life-threatening.
Is Bone marrow failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MITOXANTRONE. However, 99 reports have been filed with the FAERS database.
What Other Side Effects Does MITOXANTRONE Cause?
Febrile neutropenia (668)
Off label use (368)
Neutropenia (296)
Drug ineffective (293)
Thrombocytopenia (256)
Sepsis (240)
Pyrexia (214)
Product use in unapproved indication (177)
Disease progression (173)
Acute myeloid leukaemia (167)
What Other Drugs Cause Bone marrow failure?
CYCLOPHOSPHAMIDE (1,834)
METHOTREXATE (1,401)
ETOPOSIDE (1,081)
RITUXIMAB (1,060)
CYTARABINE (1,052)
VINCRISTINE (1,001)
DOXORUBICIN (1,000)
PALBOCICLIB (951)
CARBOPLATIN (855)
BEVACIZUMAB (835)
Which MITOXANTRONE Alternatives Have Lower Bone marrow failure Risk?
MITOXANTRONE vs MITRAGYNINE\HERBALS
MITOXANTRONE vs MIZORIBINE
MITOXANTRONE vs MOBOCERTINIB
MITOXANTRONE vs MOCLOBEMIDE
MITOXANTRONE vs MODAFINIL