NALDEMEDINE for Constipation prophylaxis: Side Effects & Safety Data
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There are 6 adverse event reports in the FDA FAERS database where NALDEMEDINE was used for Constipation prophylaxis.
Most Reported Side Effects for NALDEMEDINE
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Diarrhoea | 144 | 21.3% | 28 | 26 |
| Drug ineffective | 92 | 13.6% | 2 | 1 |
| Abdominal pain | 68 | 10.0% | 5 | 7 |
| Constipation | 47 | 6.9% | 7 | 8 |
| Nausea | 42 | 6.2% | 6 | 6 |
| Death | 28 | 4.1% | 28 | 2 |
| Malignant neoplasm progression | 27 | 4.0% | 25 | 3 |
| Vomiting | 27 | 4.0% | 0 | 8 |
| Drug withdrawal syndrome | 24 | 3.6% | 0 | 1 |
| Neoplasm malignant | 24 | 3.6% | 23 | 1 |
| Abdominal pain upper | 20 | 3.0% | 0 | 1 |
| Lung neoplasm malignant | 20 | 3.0% | 19 | 6 |
| Delirium | 18 | 2.7% | 5 | 1 |
| Drug interaction | 15 | 2.2% | 0 | 1 |
| Abdominal discomfort | 14 | 2.1% | 0 | 4 |
Other Indications for NALDEMEDINE
Other Drugs Used for Constipation prophylaxis
POLYETHYLENE GLYCOL 3350 (390)
MAGNESIUM (26)
LACTULOSE (15)
POLYETHYLENE GLYCOL 3350\POTASSIUM\SODIUM BICARBONATE\SODIUM (14)
LUBIPROSTONE (10)
BISACODYL (9)
MIRALAX (8)
DOCUSATE (7)