NALDEMEDINE for Constipation: Side Effects & Safety Data
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There are 340 adverse event reports in the FDA FAERS database where NALDEMEDINE was used for Constipation.
Most Reported Side Effects for NALDEMEDINE
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Diarrhoea | 144 | 21.3% | 28 | 26 |
| Drug ineffective | 92 | 13.6% | 2 | 1 |
| Abdominal pain | 68 | 10.0% | 5 | 7 |
| Constipation | 47 | 6.9% | 7 | 8 |
| Nausea | 42 | 6.2% | 6 | 6 |
| Death | 28 | 4.1% | 28 | 2 |
| Malignant neoplasm progression | 27 | 4.0% | 25 | 3 |
| Vomiting | 27 | 4.0% | 0 | 8 |
| Drug withdrawal syndrome | 24 | 3.6% | 0 | 1 |
| Neoplasm malignant | 24 | 3.6% | 23 | 1 |
| Abdominal pain upper | 20 | 3.0% | 0 | 1 |
| Lung neoplasm malignant | 20 | 3.0% | 19 | 6 |
| Delirium | 18 | 2.7% | 5 | 1 |
| Drug interaction | 15 | 2.2% | 0 | 1 |
| Abdominal discomfort | 14 | 2.1% | 0 | 4 |
Other Indications for NALDEMEDINE
Other Drugs Used for Constipation
POLYETHYLENE GLYCOL 3350 (9,960)
LINACLOTIDE (5,348)
NALOXEGOL OXALATE (1,418)
LACTULOSE (1,115)
BISACODYL (1,013)
POLYETHYLENE GLYCOL 3350\POTASSIUM\SODIUM BICARBONATE\SODIUM (709)
POLYETHYLENE GLYCOLS (667)
MAGNESIUM (648)
MAGNESIUM HYDROXIDE (635)
LUBIPROSTONE (563)