Does NALDEMEDINE Cause Constipation? 47 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 47 reports of Constipation have been filed in association with NALDEMEDINE (SYMPROIC). This represents 6.9% of all adverse event reports for NALDEMEDINE.
47
Reports of Constipation with NALDEMEDINE
6.9%
of all NALDEMEDINE reports
7
Deaths
8
Hospitalizations
How Dangerous Is Constipation From NALDEMEDINE?
Of the 47 reports, 7 (14.9%) resulted in death, 8 (17.0%) required hospitalization, and 2 (4.3%) were considered life-threatening.
Is Constipation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for NALDEMEDINE. However, 47 reports have been filed with the FAERS database.
What Other Side Effects Does NALDEMEDINE Cause?
Diarrhoea (144)
Drug ineffective (92)
Abdominal pain (68)
Nausea (42)
Death (28)
Malignant neoplasm progression (27)
Vomiting (27)
Drug withdrawal syndrome (24)
Neoplasm malignant (24)
Abdominal pain upper (20)
What Other Drugs Cause Constipation?
LENALIDOMIDE (9,635)
NIRAPARIB (4,128)
ADALIMUMAB (4,063)
SEMAGLUTIDE (4,036)
TIRZEPATIDE (3,417)
ERENUMAB-AOOE (3,104)
MORPHINE (2,979)
OXYCODONE (2,747)
PALBOCICLIB (2,705)
POMALIDOMIDE (2,374)
Which NALDEMEDINE Alternatives Have Lower Constipation Risk?
NALDEMEDINE vs NALMEFENE
NALDEMEDINE vs NALOXEGOL OXALATE
NALDEMEDINE vs NALOXONE
NALDEMEDINE vs NALOXONE\OXYCODONE
NALDEMEDINE vs NALOXONE\TILIDINE