NEFOPAM for Anaesthesia: Side Effects & Safety Data
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There are 54 adverse event reports in the FDA FAERS database where NEFOPAM was used for Anaesthesia.
Most Reported Side Effects for NEFOPAM
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Cholestasis | 135 | 4.7% | 2 | 72 |
| Confusional state | 134 | 4.7% | 4 | 90 |
| Acute kidney injury | 130 | 4.6% | 44 | 102 |
| Hepatocellular injury | 107 | 3.8% | 1 | 69 |
| Hepatic cytolysis | 101 | 3.5% | 0 | 72 |
| Eosinophilia | 97 | 3.4% | 23 | 76 |
| Rash maculo-papular | 97 | 3.4% | 23 | 67 |
| Drug reaction with eosinophilia and systemic symptoms | 90 | 3.2% | 10 | 62 |
| Coma | 86 | 3.0% | 4 | 50 |
| Somnolence | 84 | 2.9% | 0 | 76 |
| Agranulocytosis | 77 | 2.7% | 0 | 75 |
| Hypotension | 77 | 2.7% | 10 | 50 |
| Acute generalised exanthematous pustulosis | 75 | 2.6% | 1 | 59 |
| Toxicity to various agents | 69 | 2.4% | 31 | 37 |
| Death | 67 | 2.4% | 67 | 36 |
Other Indications for NEFOPAM
Pain (1,107)
Product used for unknown indication (614)
Analgesic therapy (115)
Procedural pain (94)
Analgesic intervention supportive therapy (81)
Pain prophylaxis (61)
Back pain (52)
Postoperative analgesia (46)
Gait disturbance (45)
General anaesthesia (45)
Other Drugs Used for Anaesthesia
PROPOFOL (2,503)
LIDOCAINE (1,064)
ROCURONIUM (875)
FENTANYL (835)
SUFENTANIL (781)
SEVOFLURANE (755)
KETAMINE (727)
BUPIVACAINE (643)
MIDAZOLAM (595)
REMIFENTANIL (483)