NEFOPAM for Pain: Side Effects & Safety Data
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There are 1,107 adverse event reports in the FDA FAERS database where NEFOPAM was used for Pain.
Most Reported Side Effects for NEFOPAM
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Cholestasis | 135 | 4.7% | 2 | 72 |
| Confusional state | 134 | 4.7% | 4 | 90 |
| Acute kidney injury | 130 | 4.6% | 44 | 102 |
| Hepatocellular injury | 107 | 3.8% | 1 | 69 |
| Hepatic cytolysis | 101 | 3.5% | 0 | 72 |
| Eosinophilia | 97 | 3.4% | 23 | 76 |
| Rash maculo-papular | 97 | 3.4% | 23 | 67 |
| Drug reaction with eosinophilia and systemic symptoms | 90 | 3.2% | 10 | 62 |
| Coma | 86 | 3.0% | 4 | 50 |
| Somnolence | 84 | 2.9% | 0 | 76 |
| Agranulocytosis | 77 | 2.7% | 0 | 75 |
| Hypotension | 77 | 2.7% | 10 | 50 |
| Acute generalised exanthematous pustulosis | 75 | 2.6% | 1 | 59 |
| Toxicity to various agents | 69 | 2.4% | 31 | 37 |
| Death | 67 | 2.4% | 67 | 36 |
Other Indications for NEFOPAM
Product used for unknown indication (614)
Analgesic therapy (115)
Procedural pain (94)
Analgesic intervention supportive therapy (81)
Pain prophylaxis (61)
Anaesthesia (54)
Back pain (52)
Postoperative analgesia (46)
Gait disturbance (45)
General anaesthesia (45)
Other Drugs Used for Pain
OXYCODONE (39,706)
FENTANYL (31,689)
MORPHINE (30,900)
BUPRENORPHINE (28,541)
ACETAMINOPHEN\OXYCODONE (27,508)
HYDROMORPHONE (27,027)
ACETAMINOPHEN\HYDROCODONE (26,494)
HYDROCODONE (23,966)
TAPENTADOL (22,976)
OXYMORPHONE (22,873)