NEFOPAM for General anaesthesia: Side Effects & Safety Data
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There are 45 adverse event reports in the FDA FAERS database where NEFOPAM was used for General anaesthesia.
Most Reported Side Effects for NEFOPAM
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Cholestasis | 135 | 4.7% | 2 | 72 |
| Confusional state | 134 | 4.7% | 4 | 90 |
| Acute kidney injury | 130 | 4.6% | 44 | 102 |
| Hepatocellular injury | 107 | 3.8% | 1 | 69 |
| Hepatic cytolysis | 101 | 3.5% | 0 | 72 |
| Eosinophilia | 97 | 3.4% | 23 | 76 |
| Rash maculo-papular | 97 | 3.4% | 23 | 67 |
| Drug reaction with eosinophilia and systemic symptoms | 90 | 3.2% | 10 | 62 |
| Coma | 86 | 3.0% | 4 | 50 |
| Somnolence | 84 | 2.9% | 0 | 76 |
| Agranulocytosis | 77 | 2.7% | 0 | 75 |
| Hypotension | 77 | 2.7% | 10 | 50 |
| Acute generalised exanthematous pustulosis | 75 | 2.6% | 1 | 59 |
| Toxicity to various agents | 69 | 2.4% | 31 | 37 |
| Death | 67 | 2.4% | 67 | 36 |
Other Indications for NEFOPAM
Pain (1,107)
Product used for unknown indication (614)
Analgesic therapy (115)
Procedural pain (94)
Analgesic intervention supportive therapy (81)
Pain prophylaxis (61)
Anaesthesia (54)
Back pain (52)
Postoperative analgesia (46)
Gait disturbance (45)
Other Drugs Used for General anaesthesia
PROPOFOL (2,292)
SEVOFLURANE (854)
ROCURONIUM (836)
SUFENTANIL (777)
FENTANYL (763)
KETAMINE (711)
REMIFENTANIL (516)
LIDOCAINE (403)
ATRACURIUM (392)
MIDAZOLAM (331)