NELARABINE for T-cell type acute leukaemia: Side Effects & Safety Data
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There are 238 adverse event reports in the FDA FAERS database where NELARABINE was used for T-cell type acute leukaemia.
Most Reported Side Effects for NELARABINE
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Febrile neutropenia | 67 | 9.1% | 6 | 40 |
| Drug ineffective | 50 | 6.8% | 14 | 10 |
| Myelopathy | 47 | 6.4% | 3 | 8 |
| Neurotoxicity | 47 | 6.4% | 10 | 14 |
| Neuropathy peripheral | 45 | 6.1% | 5 | 18 |
| Muscular weakness | 42 | 5.7% | 6 | 14 |
| Sepsis | 39 | 5.3% | 17 | 15 |
| Peripheral sensory neuropathy | 38 | 5.2% | 3 | 7 |
| Neutropenia | 37 | 5.0% | 8 | 10 |
| Off label use | 37 | 5.0% | 5 | 6 |
| Respiratory failure | 34 | 4.6% | 25 | 13 |
| Guillain-barre syndrome | 32 | 4.4% | 15 | 13 |
| Polyneuropathy | 29 | 4.0% | 1 | 5 |
| Malignant neoplasm progression | 28 | 3.8% | 17 | 6 |
| Hypoaesthesia | 27 | 3.7% | 1 | 13 |
Other Indications for NELARABINE
Acute lymphocytic leukaemia (185)
Product used for unknown indication (83)
Non-hodgkin's lymphoma (47)
Precursor t-lymphoblastic lymphoma/leukaemia (47)
T-cell lymphoma (18)
Acute lymphocytic leukaemia recurrent (14)
Precursor t-lymphoblastic lymphoma/leukaemia refractory (12)
Chemotherapy (10)
Adult t-cell lymphoma/leukaemia (8)
Precursor t-lymphoblastic leukaemia acute (7)
Other Drugs Used for T-cell type acute leukaemia
VINCRISTINE (763)
METHOTREXATE (739)
CYTARABINE (520)
DEXAMETHASONE (452)
CYCLOPHOSPHAMIDE (436)
DAUNORUBICIN (367)
DOXORUBICIN (306)
PEGASPARGASE (297)
ASPARAGINASE (282)
MERCAPTOPURINE (251)