Does NELARABINE Cause Neurotoxicity? 47 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 47 reports of Neurotoxicity have been filed in association with NELARABINE (Nelarabine). This represents 6.4% of all adverse event reports for NELARABINE.
47
Reports of Neurotoxicity with NELARABINE
6.4%
of all NELARABINE reports
10
Deaths
14
Hospitalizations
How Dangerous Is Neurotoxicity From NELARABINE?
Of the 47 reports, 10 (21.3%) resulted in death, 14 (29.8%) required hospitalization, and 5 (10.6%) were considered life-threatening.
Is Neurotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for NELARABINE. However, 47 reports have been filed with the FAERS database.
What Other Side Effects Does NELARABINE Cause?
Febrile neutropenia (67)
Drug ineffective (50)
Myelopathy (47)
Neuropathy peripheral (45)
Muscular weakness (42)
Sepsis (39)
Peripheral sensory neuropathy (38)
Neutropenia (37)
Off label use (37)
Respiratory failure (34)
What Other Drugs Cause Neurotoxicity?
AXICABTAGENE CILOLEUCEL (1,327)
OXALIPLATIN (1,272)
METHOTREXATE (1,083)
CYCLOPHOSPHAMIDE (763)
FLUOROURACIL (735)
PACLITAXEL (734)
TACROLIMUS (623)
BEVACIZUMAB (588)
VINCRISTINE (555)
CAPECITABINE (553)
Which NELARABINE Alternatives Have Lower Neurotoxicity Risk?
NELARABINE vs NELFINAVIR
NELARABINE vs NELVUTAMIG
NELARABINE vs NEMOLIZUMAB
NELARABINE vs NEMOLIZUMAB-ILTO
NELARABINE vs NEOMYCIN