Does PACLITAXEL Cause Neurotoxicity? 734 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 734 reports of Neurotoxicity have been filed in association with PACLITAXEL (PACLITAXEL PACLITAXEL). This represents 1.0% of all adverse event reports for PACLITAXEL.
734
Reports of Neurotoxicity with PACLITAXEL
1.0%
of all PACLITAXEL reports
43
Deaths
100
Hospitalizations
How Dangerous Is Neurotoxicity From PACLITAXEL?
Of the 734 reports, 43 (5.9%) resulted in death, 100 (13.6%) required hospitalization, and 22 (3.0%) were considered life-threatening.
Is Neurotoxicity Listed in the Official Label?
Yes, Neurotoxicity is listed as a known adverse reaction in the official FDA drug label for PACLITAXEL.
What Other Side Effects Does PACLITAXEL Cause?
Neutropenia (4,553)
Nausea (4,521)
Dyspnoea (4,519)
Diarrhoea (4,289)
Off label use (4,075)
Anaemia (3,949)
Neuropathy peripheral (3,508)
Malignant neoplasm progression (3,484)
Fatigue (3,418)
Death (3,143)
What Other Drugs Cause Neurotoxicity?
AXICABTAGENE CILOLEUCEL (1,327)
OXALIPLATIN (1,272)
METHOTREXATE (1,083)
CYCLOPHOSPHAMIDE (763)
FLUOROURACIL (735)
TACROLIMUS (623)
BEVACIZUMAB (588)
VINCRISTINE (555)
CAPECITABINE (553)
BLINATUMOMAB (530)
Which PACLITAXEL Alternatives Have Lower Neurotoxicity Risk?
PACLITAXEL vs PACRITINIB
PACLITAXEL vs PALBOCICLIB
PACLITAXEL vs PALIPERIDONE
PACLITAXEL vs PALIVIZUMAB
PACLITAXEL vs PALONOSETRON