Does VINCRISTINE Cause Neurotoxicity? 555 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 555 reports of Neurotoxicity have been filed in association with VINCRISTINE (VinCRIStine Sulfate). This represents 0.8% of all adverse event reports for VINCRISTINE.
555
Reports of Neurotoxicity with VINCRISTINE
0.8%
of all VINCRISTINE reports
89
Deaths
124
Hospitalizations
How Dangerous Is Neurotoxicity From VINCRISTINE?
Of the 555 reports, 89 (16.0%) resulted in death, 124 (22.3%) required hospitalization, and 36 (6.5%) were considered life-threatening.
Is Neurotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for VINCRISTINE. However, 555 reports have been filed with the FAERS database.
What Other Side Effects Does VINCRISTINE Cause?
Febrile neutropenia (8,676)
Off label use (6,562)
Disease progression (5,252)
Neutropenia (4,982)
Drug ineffective (4,084)
Pyrexia (3,460)
Product use in unapproved indication (3,073)
Thrombocytopenia (2,940)
Sepsis (2,791)
Anaemia (2,603)
What Other Drugs Cause Neurotoxicity?
AXICABTAGENE CILOLEUCEL (1,327)
OXALIPLATIN (1,272)
METHOTREXATE (1,083)
CYCLOPHOSPHAMIDE (763)
FLUOROURACIL (735)
PACLITAXEL (734)
TACROLIMUS (623)
BEVACIZUMAB (588)
CAPECITABINE (553)
BLINATUMOMAB (530)
Which VINCRISTINE Alternatives Have Lower Neurotoxicity Risk?
VINCRISTINE vs VINDESINE
VINCRISTINE vs VINORELBINE
VINCRISTINE vs VINORELBINE\VINORELBINE
VINCRISTINE vs VIREAD
VINCRISTINE vs VISIPAQUE