Does AXICABTAGENE CILOLEUCEL Cause Neurotoxicity? 1,327 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 1,327 reports of Neurotoxicity have been filed in association with AXICABTAGENE CILOLEUCEL (YESCARTA). This represents 15.4% of all adverse event reports for AXICABTAGENE CILOLEUCEL.
1,327
Reports of Neurotoxicity with AXICABTAGENE CILOLEUCEL
15.4%
of all AXICABTAGENE CILOLEUCEL reports
239
Deaths
615
Hospitalizations
How Dangerous Is Neurotoxicity From AXICABTAGENE CILOLEUCEL?
Of the 1,327 reports, 239 (18.0%) resulted in death, 615 (46.3%) required hospitalization, and 98 (7.4%) were considered life-threatening.
Is Neurotoxicity Listed in the Official Label?
Yes, Neurotoxicity is listed as a known adverse reaction in the official FDA drug label for AXICABTAGENE CILOLEUCEL.
What Other Side Effects Does AXICABTAGENE CILOLEUCEL Cause?
Cytokine release syndrome (4,140)
Immune effector cell-associated neurotoxicity syndrome (1,821)
Pyrexia (859)
Death (756)
Disease progression (745)
Hypotension (398)
Neutropenia (391)
Confusional state (299)
Encephalopathy (292)
Diffuse large b-cell lymphoma (291)
What Other Drugs Cause Neurotoxicity?
OXALIPLATIN (1,272)
METHOTREXATE (1,083)
CYCLOPHOSPHAMIDE (763)
FLUOROURACIL (735)
PACLITAXEL (734)
TACROLIMUS (623)
BEVACIZUMAB (588)
VINCRISTINE (555)
CAPECITABINE (553)
BLINATUMOMAB (530)
Which AXICABTAGENE CILOLEUCEL Alternatives Have Lower Neurotoxicity Risk?
AXICABTAGENE CILOLEUCEL vs AXITINIB
AXICABTAGENE CILOLEUCEL vs AZACITIDINE
AXICABTAGENE CILOLEUCEL vs AZATHIOPRINE
AXICABTAGENE CILOLEUCEL vs AZD-1222
AXICABTAGENE CILOLEUCEL vs AZELAIC ACID